Chromosomal Inheritance

AP Biology· difficulty 4/5

A student crosses true-breeding white-eyed Drosophila females with red-eyed males. The reciprocal cross uses red-eyed females and white-eyed males. F1 from cross 1: all females red-eyed, all males white-eyed. F1 from cross 2: all F1 red-eyed regardless of sex.

What does this pattern reveal?

  • A

    Maternal cytoplasmic inheritance

  • B

    Y-linked inheritance

  • C

    The eye-color gene is X-linked recessive (red dominant)

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  • D

    The gene is autosomal recessive

Explanation

The reciprocal-cross asymmetry (results differ depending on which parent carries which allele) is the hallmark of sex linkage. White-mother x red-father gives white sons (XwY) and red daughters (XwXr) - classic X-linked recessive.

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