Insertion or deletion of a single nucleotide (not a multiple of 3) causes
- A
A missense mutation, swapping one amino acid for another at a single position
- B
A nonsense mutation, creating a premature stop codon at the insertion site
- Ccheck_circle
A frameshift, altering the reading frame and changing all subsequent codons
- D
A silent mutation, leaving the encoded amino acids and protein function unchanged
Explanation
Frameshift mutations typically have severe effects, usually producing nonfunctional truncated or scrambled proteins.