Mutations

AP Biology· difficulty 1/5

WT: ATG-AAA-CCC-TAA A: ATG-AAG-CCC-TAA B: ATG-AAA-CCC-TAG (early stop) C: ATG-AAA-CCT-AAA D: ATG-AAA-ACC-CTA-A Compare to WT

Which mutant most likely results in a frameshift?

  • A

    A

  • B

    D

    check_circle
  • C

    B

  • D

    C

Explanation

Mutant D inserts an extra base (A) after AAA, shifting the downstream reading frame. Mutant A is silent/missense, B is nonsense (premature stop), C is a single-base substitution that does not change frame.

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