Changes one nucleotide so the codon encodes a different amino acid Sickle-cell anemia is caused by a missense mutation: glutamic acid → valine at position 6 of β-globin.

Changes one nucleotide so the codon still encodes the same amino acid

Changes one nucleotide so the codon becomes a premature stop signal

Deletes one nucleotide, shifting the reading frame for downstream codons

Changes one nucleotide so the codon encodes a different amino acid

Mutations

AP Biology· difficulty 2/5

A missense mutation

A
$Changes one nucleotide so the codon still encodes the same amino acid$
B
$Changes one nucleotide so the codon becomes a premature stop signal$
C
$Deletes one nucleotide, shifting the reading frame for downstream codons$
D
$Changes one nucleotide so the codon encodes a different amino acid$
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Explanation

Sickle-cell anemia is caused by a missense mutation: glutamic acid \to valine at position 6 of β-globin.

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