Columbian Exchange, Spanish Exploration, and Conquest

AP US History· difficulty 3/5

The most devastating consequence of European contact for Native Americans was

  • A

    Loss of ancestral lands through European treaties and conquest

  • B

    Forced relocation westward and onto reservations by colonists

  • C

    Forced religious conversion to Catholicism by Spanish missionaries

  • D

    Disease epidemics (smallpox, measles, etc.) that killed up to 90% in some regions

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Explanation

Lacking immunity, Native populations suffered catastrophic mortality, fundamentally altering the demographic balance of the Americas.

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