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Henderson-Hasselbalch Equation

AP Chemistry· difficulty 3/5

Acid pKa HCOOH 3.7 CH3COOH 4.7 H2PO4- 7.2

Which acid is best for designing a buffer at pH 7.0?

  • A

    H2PO4-/HPO4^2-

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  • B

    CH3COOH/CH3COO-

  • C

    Any of the three

  • D

    HCOOH/HCOO-

Explanation

A buffer works best within +/-1 pH unit of its pKa. pKa 7.2 is closest to pH 7.0.

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