Replication

AP Biology· difficulty 2/5

Why do eukaryotic chromosomes use multiple origins of replication rather than a single one?

  • A

    Eukaryotic helicases unwind DNA too slowly without multiple cooperating starting sites

  • B

    Eukaryotic origins are inefficient and need backup sites to ensure replication completes

  • C

    Eukaryotic chromosomes adopted this strategy from bacteria for faster replication speed

  • D

    Eukaryotic genomes are too large to copy from a single origin in a reasonable time

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Explanation

Multiple origins replicate in parallel, so a 10⁹ bp human genome can be copied in a few hours.

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