Replication

AP Biology· difficulty 2/5

DNA ligase functions to

A
$Unwind the DNA double helix ahead of the advancing replication fork$
B
$Seal the gap between Okazaki fragments by forming phosphodiester bonds$
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C
$Cut DNA strands at specific sequences to allow recombination events$
D
$Add short RNA primers to initiate synthesis of new DNA strands$

Explanation

Ligase joins the 3'-OH and 5'-phosphate ends of adjacent DNA fragments, completing the lagging strand.

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