Replication

AP Biology· difficulty 3/5

The lagging strand is synthesized

A
$Discontinuously, in short Okazaki fragments away from the fork$
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B
$By RNA polymerase, which adds ribonucleotides instead of deoxyribonucleotides$
C
$In the 5' to 3' direction, moving directly toward the helicase enzyme$
D
$Continuously, as one long strand toward the replication fork$

Explanation

Because DNA polymerase only synthesizes 5'\to3', the lagging strand must be made in pieces (Okazaki fragments) that are later joined.

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