Regulation of Cell Cycle

AP Biology· difficulty 3/5

Two culture dishes show the behavior of cells once they cover the substrate.

Normal: monolayer Cancer: piles up

The contrast in the two dishes is best explained by:

  • A

    Loss of contact (density-dependent) inhibition in cancer cells

    check_circle
  • B

    Faster S phase in normal cells

  • C

    Apoptosis of cancer cells

  • D

    Mitotic spindle malfunction in normal cells

Explanation

Normal cells stop dividing on contact with neighbors and form a monolayer. Cancer cells override this signal and grow on top of one another.

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