Pepsin (stomach enzyme) and trypsin (intestinal enzyme) have different pH optima because
- A
The stomach maintains a higher pH than the intestine, so pepsin needs basic conditions
- B
Random variation in amino acid sequence makes their pH preferences unpredictable
- Ccheck_circle
Each enzyme's structure and active-site chemistry are tuned to its physiological location's pH
- D
All enzymes work the same way regardless of pH because the active site is universal
Explanation
Stomach pH ~2 selects for pepsin's optimum near 2; intestinal pH ~8 selects for trypsin's optimum near 8.