Enzyme Catalysis

AP Biology· difficulty 2/5

[substrate] rate

The rate plateau at high substrate concentration occurs because

  • A

    All cofactors become tightly bound to substrate

  • B

    Allosteric inhibitors fully occupy regulatory sites

  • C

    Active sites change shape at high concentrations

  • D

    All enzyme active sites become saturated with substrate

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Explanation

Once every active site is occupied, additional substrate cannot further increase the reaction rate (V_max).

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