Receptor tyrosine kinases respond to ligand binding by
- A
Opening their ion channel pore, which then allows calcium influx and second-messenger signaling
- Bcheck_circle
Dimerizing and autophosphorylating tyrosine residues, creating docking sites for relay proteins
- C
Cleaving an intracellular fragment, which then translocates to the nucleus to regulate gene expression
- D
Activating an associated G protein, which then triggers the cytoplasmic adenylyl cyclase enzyme
Explanation
Activated RTKs dimerize, cross-phosphorylate tyrosines, and recruit multiple downstream signaling proteins simultaneously.