Non-Mendelian Genetics

AP Biology· difficulty 3/5

Blood-type frequencies in a population are A = 41 percent, B = 9 percent, AB = 4 percent, O = 46 percent. Allele frequencies must sum (p + q + r = 1) and population is in Hardy-Weinberg equilibrium for ABO.

Phenotype Frequency A 0.41 B 0.09 AB 0.04 O 0.46

What is the frequency of the i (O) allele?

  • A

    0.68

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  • B

    0.32

  • C

    0.21

  • D

    0.46

Explanation

Type O is homozygous ii so freq(ii) = i^2 = 0.46. Therefore i = sqrt(0.46) ~ 0.68.

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