Non-Mendelian Genetics

AP Biology· difficulty 3/5

A genetic disease has incomplete penetrance. Of 100 individuals with the disease genotype, only 80 actually exhibit the disease.

Status Count Genotype + 100 Phenotype + 80

What is the penetrance of this disease allele?

  • A

    Cannot be determined.

  • B

    80%

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  • C

    20%

  • D

    100%

Explanation

Penetrance = (# with phenotype)/(# with genotype) = 80/100 = 80 percent.

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