Chromosomal Inheritance

AP Biology· difficulty 3/5

A cross of red-eye female (X^R X^R) x white-eye male (X^r Y) Drosophila produced 200 offspring. F1 was self-crossed and F2 phenotypes recorded.

F2 phenotype Count Red female 100 Red male 50 White male 50

Why are no white-eye females observed?

  • A

    White-eye allele is lethal in females.

  • B

    F1 females are heterozygous (X^R X^r); none of the F2 females inherits two recessive alleles.

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  • C

    Mutation rate differs between sexes.

  • D

    Males alone carry the white allele.

Explanation

F1 females are X^R X^r and F1 males are X^R Y. Among F2: X^R X^R, X^R X^r, X^R Y, X^r Y. No X^r X^r is produced from this F1, so no white-eye females appear.

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