Chromosomal Inheritance

AP Biology· difficulty 3/5

A genetic map shows four loci A, B, C, D arranged on a chromosome with map distances 9 mu (A-B), 8 mu (B-C), and 11 mu (C-D).

A B C D 9 mu 8 mu 11 mu Recombination frequencies between adjacent loci

What is the predicted recombination frequency between loci A and D, assuming additivity?

  • A

    Approximately 28%

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  • B

    Less than 1%

  • C

    Approximately 11%

  • D

    Exactly 50%

Explanation

Map distances are additive over short intervals: 9 + 8 + 11 = 28 mu, corresponding to ~28% recombination. Distances above 50 cM saturate at 50%.

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