The cytological basis of independent assortment is
- A
Crossing over between homologous chromosomes during prophase I
- B
Random alignment of sister chromatids at the metaphase plate in mitosis
- C
Cleavage of the cytoplasm during the cytokinesis stage of cell division
- Dcheck_circle
Random orientation of homologous chromosome pairs at metaphase I
Explanation
Each tetrad orients independently at the metaphase plate; this produces 2ⁿ different gamete combinations from chromosome sorting alone.