AP Biology · Topic 5.2

Meiosis and Genetic Diversity Practice

Part of Heredity.(IST-1.D)

Practice questions

6

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Sample questions

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  1. Sample 1difficulty 2/5

    Two homologous chromosomes (maternal and paternal) are paired in a synaptonemal complex; non-sister chromatids overlap at a chiasma where DNA is exchanged.

    Maternal Paternal Chiasma Synaptonemal complex aligns homologs

    Which best describes the genetic outcome of the event diagrammed?

    • A

      Recombinant chromatids carry new combinations of maternal and paternal alleles.

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    • B

      Sister chromatids exchange identical DNA, producing no genetic change.

    • C

      Centromeres are duplicated, doubling chromosome number.

    • D

      The cell becomes polyploid as a result of unequal crossover.

    Why

    Crossing over at the chiasma swaps homologous (non-sister) chromatid segments, producing recombinant chromatids that combine alleles from both parents and increasing genetic diversity.

  2. Sample 2difficulty 2/5

    Crossing over (genetic recombination) occurs during _______ of meiosis I.

    • A

      Telophase I (when nuclear envelopes begin to reform)

    • B

      Anaphase I (when homologous chromosomes separate)

    • C

      Prophase I (when homologs synapse and exchange segments)

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    • D

      Cytokinesis (when the cytoplasm divides into two)

    Why

    Tetrads form during prophase I; chromatids exchange segments at chiasmata, mixing maternal and paternal alleles.

  3. Sample 3difficulty 2/5

    Mendel's law of independent assortment states that

    • A

      All gametes produced by a heterozygous parent carry identical allele combinations

    • B

      Alleles of different genes (on different chromosomes) sort independently into gametes

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    • C

      The two alleles for a single gene separate from each other during gamete formation

    • D

      Genes located near each other on the same chromosome are always inherited together

    Why

    During meiosis, each homologous pair orients independently — different genes on different chromosomes assort independently.

  4. Sample 4difficulty 3/5

    The three main sources of genetic variation in sexually reproducing organisms are

    • A

      DNA repair, RNA splicing, post-translational modification

    • B

      Mitosis, cytokinesis, binary fission

    • C

      Crossing over, independent assortment, random fertilization

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    • D

      DNA replication, transcription, translation

    Why

    All three operate during/around meiosis and reproduction; mutations are an additional source over generations.

  5. Sample 5difficulty 3/5

    The cytological basis of independent assortment is

    • A

      Crossing over between homologous chromosomes during prophase I

    • B

      Random alignment of sister chromatids at the metaphase plate in mitosis

    • C

      Cleavage of the cytoplasm during the cytokinesis stage of cell division

    • D

      Random orientation of homologous chromosome pairs at metaphase I

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    Why

    Each tetrad orients independently at the metaphase plate; this produces 2ⁿ different gamete combinations from chromosome sorting alone.