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Non-Mendelian Genetics

AP Biology· difficulty 4/5

Two unaffected parents have an affected daughter for an autosomal recessive disease. The probability that an unaffected sibling is a carrier is

  • A

    23\frac{2}{3}

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  • B

    34\frac{3}{4}

  • C

    12\frac{1}{2}

  • D

    14\frac{1}{4}

Explanation

Both parents are Aa. Among unaffected offspring (1 AA : 2 Aa), P(Aa | unaffected) = 2/3.

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