Regulation of Gene Expression

AP Biology· difficulty 3/5

Histone acetylation generally

A
$Triggers DNA replication at origins$
B
$Loosens chromatin and promotes transcription$
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C
$Cleaves nucleosomes from DNA strands$
D
$Compacts chromatin and represses transcription$

Explanation

Acetyl groups neutralize histone tail charges, weakening DNA-histone interactions and opening chromatin.

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