Regulation of Gene Expression

AP Biology· difficulty 3/5

DNA methylation (e.g., 5-methylcytosine in CpG islands) generally

A
$Activates transcription$
B
$Represses transcription$
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C
$Increases mutation$
D
$Cleaves DNA$

Explanation

Methylation typically silences gene expression, often associated with X-inactivation, imprinting, and tumor suppressor silencing in cancer.

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