Replication

AP Biology· difficulty 3/5

Telomerase is a special DNA polymerase that

  • A

    Cleaves DNA at telomeric repeat sequences during chromosome condensation

  • B

    Extends telomeres at chromosome ends, using its own RNA as a template

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  • C

    Replicates circular plasmid DNA in bacterial cells, using a DNA template

  • D

    Synthesizes mRNA transcripts from telomeric DNA, using ribonucleotides

Explanation

Telomerase contains an RNA template; without it, chromosomes shorten with each replication. Active in stem cells, germ cells, and most cancers.

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