A loss-of-function mutation in the activator's DNA-binding domain would most likely cause:
- A
Translation of an unrelated mRNA.
- B
Increased transcription via positive feedback.
- Ccheck_circle
Decreased transcription of target genes due to failure of activator recruitment.
- D
No change in transcription.
Explanation
If the activator cannot bind the enhancer, it cannot recruit/coactivate RNA Pol II at the promoter, decreasing transcription of its target genes.