Biotechnology

AP Biology· difficulty 3/5

A polymerase chain reaction begins with one DNA template molecule. Standard primers, Taq polymerase, and dNTPs are present.

Denature 95C Anneal 55C Extend 72C repeat ~30 cycles Yield: 2^n copies

Theoretically, how many double-stranded copies of the target sequence are produced after 30 cycles?

  • A

    Approximately 60

  • B

    Approximately 2 x 30 = 60

  • C

    Approximately 30

  • D

    Approximately 2^30 (about 1 billion)

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Explanation

Each PCR cycle ideally doubles the target DNA. Starting from one molecule, 30 cycles produce <del>2^30 (</del>10^9) copies, illustrating exponential amplification.

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