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Chromosomal Inheritance

AP Biology· difficulty 2/5

A female heterozygous carrier of the X-linked recessive hemophilia allele (X^H X^h) is crossed with an unaffected male (X^H Y).

Cross: X^H X^h x X^H Y X^HY X^HX^h X^H X^HX^H Y X^H X^hX^h Y h = hemophilia (recessive) Mother is carrier; father unaffected

What is the probability that a son from this cross will be affected with hemophilia?

  • A

    1/4

  • B

    0

  • C

    1

  • D

    1/2

    check_circle

Explanation

Among male offspring, half inherit X^H (unaffected) and half inherit X^h (affected). So 50% of sons are predicted to be hemophiliacs.

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