Non-Mendelian Genetics

AP Biology· difficulty 2/5

The ABO blood group is determined by three alleles. Heterozygotes I^A I^B express both A and B antigens on red blood cells.

ABO Blood Group Alleles Genotype Phenotype I^A I^A or I^A i A I^B I^B or I^B i B I^A I^B AB i is recessive to I^A and I^B

Why is the AB phenotype an example of both codominance and multiple alleles?

  • A

    I^A and I^B are X-linked alleles producing the AB phenotype.

  • B

    Only one allele is expressed; the gene has only two alleles.

  • C

    The heterozygote shows an intermediate blood type.

  • D

    Both I^A and I^B are expressed simultaneously, and three alleles (I^A, I^B, i) exist for the gene.

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Explanation

The ABO gene has three possible alleles (multiple alleles). In an I^A I^B heterozygote, both A and B antigens are produced, illustrating codominance.

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