Introduction to Signal Transduction

AP Biology· difficulty 3/5

closed ligand open ions flow when ligand binds

A ligand-gated ion channel transduces a signal by:

  • A

    Opening to allow specific ions to cross the membrane

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  • B

    Hydrolyzing GTP

  • C

    Phosphorylating itself on tyrosines

  • D

    Activating intracellular kinases first

Explanation

Binding of the ligand causes a conformational change that opens an ion-selective pore, allowing rapid ion flow that changes membrane potential or signaling.

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