The graph shows the parallel concentrations of mitotic cyclin (dashed) and active MPF (solid).
What best explains MPF activity dropping while cyclin already began declining?
- A
CDK levels rise sharply at anaphase
- Bcheck_circle
Cyclin degradation by APC/C inactivates the CDK partner
- C
ATP supply drops during mitosis
- D
MPF is independent of cyclin
Explanation
The Anaphase-Promoting Complex tags mitotic cyclin for destruction; loss of cyclin inactivates CDK1 (the kinase part of MPF), allowing exit from mitosis.