Regulation of Cell Cycle

AP Biology· difficulty 3/5

[cyclin] cell cycle time → M phase S phase

Mitotic cyclin levels are highest just before which event?

  • A

    End of cytokinesis

  • B

    Entry into S phase

  • C

    Beginning of G1

  • D

    Entry into mitosis (G2/M transition)

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Explanation

Mitotic cyclin accumulates during G2 and peaks at G2/M, where it binds CDK1 to form MPF and trigger entry into mitosis. It is then degraded during anaphase.

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