Regulation of Cell Cycle

AP Biology· difficulty 3/5

Three checkpoints monitor the integrity of the cell cycle.

The G1/S (restriction) checkpoint primarily checks for:

A
$Completion of cytokinesis$
B
$Proper chromosome attachment to spindle fibers$
C
$Telomere shortening only$
D
$DNA damage and adequate cell size/nutrients before committing to replication$
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Explanation

The G1/S restriction checkpoint integrates signals about DNA damage, cell size, growth factors, and nutrients before allowing entry into S phase.

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