Pulse-chase experiments label proteins with radioactive amino acids and track their movement through cellular compartments. The label appears first in the rough ER, then in the cis Golgi, then trans Golgi, then in secretory vesicles.
What is the major role of the Golgi apparatus in the pathway above?
- A
Replicating cellular DNA
- B
Translating mRNA into protein
- Ccheck_circle
Modifying, sorting, and packaging proteins for delivery to their destinations
- D
Generating ATP for the cell
Explanation
The Golgi receives ER vesicles, modifies their cargo (e.g., glycosylation), sorts them at the trans face, and dispatches them via vesicles to membranes, lysosomes, or secretion.