Cells that secrete large amounts of protein (such as pancreatic acinar cells) are characterized by abundant rough ER. Why?
- A
Smooth ER lacks lipids needed for protein folding
- B
Rough ER replicates DNA before secretion
- C
Smooth ER converts proteins into carbohydrates for export
- Dcheck_circle
Ribosomes on rough ER synthesize proteins that enter the ER lumen for processing and export
Explanation
Rough ER ribosomes thread newly synthesized polypeptides into the ER lumen, where they fold, are modified, and are packaged for secretion.