Regulation of Cell Cycle

AP Biology· difficulty 2/5

Cancer cells differ from normal cells in that they

A
$Always trigger apoptosis when DNA damage is detected at checkpoints$
B
$Die after a single division due to telomere shortening$
C
$Lose normal cell-cycle regulation, divide uncontrollably, and ignore checkpoints$
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D
$Cannot replicate their DNA, so they accumulate in G₁ phase$

Explanation

Mutations in genes regulating the cycle (proto-oncogenes, tumor suppressors) free cancer cells from normal growth controls.

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