Regulation of Cell Cycle

AP Biology· difficulty 3/5

The metaphase (spindle assembly) checkpoint ensures

A
$Cytokinesis has produced two genetically identical daughter cells$
B
$All chromosomes are attached to spindle fibers from both poles before anaphase begins$
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C
$DNA replication is complete and chromosomes are undamaged$
D
$All chromosomes are condensed and visible under a light microscope$

Explanation

Unattached kinetochores send a "wait" signal; once all are properly bipolar-attached, anaphase proceeds.

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