Heating an enzyme often abolishes its activity because heat
- A
Removes the bound water shell around the enzyme, exposing its hydrophobic protein interior
- B
Adds new amino-acid residues to the polypeptide, lengthening the active enzyme structure
- C
Cleaves the strong peptide bonds connecting amino acids in the linear polypeptide chain
- Dcheck_circle
Disrupts the weak interactions that maintain higher-order folding (denatures it)
Explanation
Denaturation breaks the H-bonds, ionic interactions, and hydrophobic contacts that hold the active conformation, leaving the primary sequence intact but inactive.