AP Biology · Topic 1.5
Structure and Function of Biological Macromolecules Practice
Part of Chemistry of Life.(SYI-1.E)
Practice questions
20
Sample questions
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Sample 1difficulty 2/5
The <strong>primary</strong> structure of a protein refers to
- A
Its alpha helices and beta sheets
- B
Its three-dimensional folded shape
- Ccheck_circle
Its sequence of amino acids
- D
Multi-subunit assemblies
Why
Primary = sequence; secondary = local folds (helices/sheets); tertiary = overall 3D shape; quaternary = multi-chain assembly.
- A
Sample 2difficulty 2/5
Triglycerides serve as long-term energy storage primarily because
- A
Their nitrogen-rich tails store energy more densely than sugars
- B
Their highly oxidized C-O bonds release ATP faster than glycogen
- C
Their polar ester linkages dissolve readily in cytosolic water
- Dcheck_circle
Their highly reduced C-H bonds release more ATP per gram than carbohydrates
Why
Lipids are more reduced (more C-H bonds) than carbs/proteins, so full oxidation releases ~9 kcal/g vs ~4 kcal/g for carbohydrates.
- A
Sample 3difficulty 2/5
A peptide bond forms between
- A
Two carboxyl groups of adjacent residues
- B
A sulfhydryl group and an amino group
- C
A hydroxyl group and a phosphate group
- Dcheck_circle
An amino group and a carboxyl group
Why
The amino (-NH₂) of one amino acid joins the carboxyl (-COOH) of another via dehydration synthesis.
- A
Sample 4difficulty 2/5
A triglyceride consists of
- Acheck_circle
Glycerol + three fatty acids
- B
Three nucleotides
- C
Three glucose molecules
- D
A glycerol + phosphate + two fatty acids
Why
Glycerol provides three -OH groups to which three fatty acids are esterified.
- A
Sample 5difficulty 2/5
All steroids share what structural feature?
- A
A phosphate-sugar repeating backbone
- B
A long fatty-acid hydrocarbon tail
- Ccheck_circle
A four-fused-ring carbon skeleton
- D
A polypeptide chain of amino acids
Why
The four-ring (three 6-carbon, one 5-carbon) sterol skeleton, with different side groups giving cholesterol, testosterone, etc.
- A