Boundaries: Punctuation and Sentence Structure

SAT Reading and Writing· difficulty 2/5

Following the discovery of penicillin in 1928 ______ the development of antibiotics transformed twentieth-century medicine.

Which choice completes the text so that it conforms to the conventions of Standard English?

Explanation

The introductory prepositional phrase "Following the discovery of penicillin in 1928" should be followed by a comma.

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