Phylogeny

AP Biology· difficulty 3/5

A second protein, hemoglobin, gives different percent identities than cytochrome c for the same five species. Hemoglobin shows 99 percent (chimp), 86 (mouse), 70 (chicken), 50 (tuna), and 5 (yeast).

Species % Identity chimp mouse chicken yeast cytC Hb

Why is cytochrome c more conserved across species than hemoglobin?

  • A

    Yeast lack DNA, biasing the comparison.

  • B

    Cytochrome c performs a fundamental role in respiration shared by nearly all eukaryotes; selection eliminates most variants.

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  • C

    Hemoglobin is not a protein, so it cannot be sequenced.

  • D

    Hemoglobin evolves before cytochrome c.

Explanation

Highly conserved proteins typically perform essential, ancient functions where most mutations are deleterious; cytochrome c is a core component of the electron transport chain.

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