Mendelian Genetics

AP Biology· difficulty 3/5

In the same pedigree, individual III-2 (an unaffected male) plans to have a child with a known carrier (Aa). Both parents of III-2 are also carriers (Aa).

What is the probability that III-2 and his Aa partner have an affected (aa) child?

A
$1/6$
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B
$2/3$
C
$1/4$
D
$1/2$

Explanation

P(III-2 is Aa) = 2/3. P(child aa | both Aa) = 1/4. Combined: 2/3 x 1/4 = 1/6.

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