Translation

AP Biology· difficulty 3/5

During translation, the peptide bond is formed

  • A

    By spontaneous condensation between adjacent amino acids in the A site

  • B

    By aminoacyl-tRNA synthetase activity charging tRNAs with amino acids

  • C

    By peptidyl transferase activity of the large ribosomal subunit (rRNA)

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  • D

    By GTP hydrolysis catalyzed by elongation factor EF-Tu in the ribosome

Explanation

The 23S rRNA in bacteria (28S in eukaryotes) catalyzes peptide bond formation — making the ribosome a ribozyme.

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