Chromosomal Inheritance

AP Biology· difficulty 3/5

An unaffected father (square, empty) and a carrier mother (circle with central dot) have three sons; two are affected, one is unaffected. No daughters are affected.

Carrier female: dot Affected: filled Affected sons from carrier mother

Which inheritance pattern is most consistent with this pedigree?

  • A

    Mitochondrial

  • B

    Y-linked

  • C

    Autosomal dominant

  • D

    X-linked recessive

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Explanation

A carrier mother passes X^a to ~50% of her sons, who are hemizygous and affected; daughters are mostly carriers/unaffected. This is classic X-linked recessive inheritance.

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