Signal Transduction

AP Biology· difficulty 2/5

A signaling cascade with multiple kinase steps amplifies the signal because

  • A

    Each kinase irreversibly converts itself into product, ensuring permanent activation of the response

  • B

    Each kinase activates only one downstream substrate, but the pathway is extremely fast at every stage

  • C

    Each kinase phosphorylates many target molecules, multiplying the response at each step

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  • D

    Each kinase moves into the nucleus directly, where it acts as a transcription factor at every step

Explanation

A few activated receptors → many activated kinases → many more phosphorylated targets. Tiny signals can produce massive responses.

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