In an aqueous environment, hydrophobic amino-acid side chains tend to be located
- A
Exposed on the protein surface, in contact with water
- B
Always clustered along the central α-helix axis
- C
Concentrated near the N-terminus of the polypeptide
- Dcheck_circle
Buried in the protein's interior, away from water
Explanation
Burying hydrophobic side chains releases ordered water molecules, increasing entropy — the "hydrophobic effect" drives folding.