AP Biology · Topic 5.1

Meiosis Practice

Part of Heredity.(IST-1.C)

Practice questions

10

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Sample questions

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  1. Sample 1difficulty 1/5

    Mitotic metaphase Meiosis I metaphase Sister-chromatid pairs single file Tetrads (homologous pairs)

    Which difference in chromosome alignment correctly distinguishes mitotic metaphase from meiotic metaphase I?

    • A

      Both align identical structures.

    • B

      Mitosis aligns individual replicated chromosomes; meiosis I aligns homologous chromosome pairs (tetrads).

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    • C

      Mitosis aligns tetrads; meiosis I aligns single chromosomes.

    • D

      Mitosis lacks centromere attachment to spindle.

    Why

    In mitotic metaphase, each replicated chromosome aligns singly. In metaphase I, homologous pairs synapse as tetrads and align together, enabling later separation of homologs.

  2. Sample 2difficulty 1/5

    Human somatic cells have 46 chromosomes (2n). Human gametes have

    • A

      46 (2n)

    • B

      1

    • C

      23 (n)

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    • D

      92 (4n)

    Why

    Haploid n = 23. Fertilization restores the diploid number (46) in the zygote.

  3. Sample 3difficulty 1/5

    Meiosis is the form of cell division that

    • A

      Produces somatic cells for growth and repair

    • B

      Produces 2 genetically identical diploid cells

    • C

      Repairs damaged DNA via homologous recombination

    • D

      Produces 4 genetically diverse haploid cells (gametes/spores)

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    Why

    Meiosis halves chromosome number and shuffles alleles, producing haploid cells that fuse during fertilization.

  4. Sample 4difficulty 2/5

    The diagram shows a cell with homologous chromosomes paired as tetrads aligned along the equator before separation.

    Stage X Homologs paired on metaphase plate Key features: - Tetrads aligned - Independent assortment occurs - Spindle attached to centromeres

    Which stage of meiosis is depicted, and what genetic process establishes independent assortment here?

    • A

      Metaphase I; random orientation of homologous pairs determines independent assortment.

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    • B

      Prophase II; nuclear envelope reforms around chromosomes.

    • C

      Anaphase I; sister chromatids separate to opposite poles.

    • D

      Metaphase II; sister chromatids align independently.

    Why

    During metaphase I, homologous chromosome pairs (tetrads) line up at the metaphase plate. Their random maternal/paternal orientation gives rise to independent assortment, the foundation of Mendel's second law.

  5. Sample 5difficulty 2/5

    The diagram contrasts the products of mitosis and meiosis from a 2n parent cell.

    Mitosis Meiosis 2n 2n 2n 2n n n n n

    Which statement best describes the difference shown?

    • A

      Mitosis produces gametes; meiosis produces somatic cells.

    • B

      Meiosis produces four haploid (n) cells via two divisions; mitosis produces two diploid (2n) cells.

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    • C

      Mitosis halves chromosome number while meiosis doubles it.

    • D

      Both processes produce four haploid cells, but only mitosis includes crossing over.

    Why

    Mitosis yields two diploid daughter cells genetically identical to the parent; meiosis includes two divisions and yields four haploid cells with new allelic combinations from independent assortment and crossing over.