AP Biology · Topic 2.3

Cell Size Practice

Part of Cell Structure and Function.(ENE-1.C)

Practice questions

7

Want a predicted score for the whole AP BIO exam? Take the 20-question diagnostic and Lumi will plan the rest.

Sample questions

5 of 7 — sign in to practice the rest with adaptive difficulty and mastery tracking.

  1. Sample 1difficulty 2/5

    Cells are typically small because as they grow,

    • A

      Membranes thicken and progressively block the diffusion of nutrients inward across the surface

    • B

      Surface area increases faster than volume, overwhelming transport

    • C

      Volume increases faster than surface area, limiting exchange across membranes

      check_circle
    • D

      DNA replication slows down dramatically as cytoplasmic volume expands inside the cell

    Why

    Volume scales with r³ but surface area with r². Larger cells can't move enough material across their membranes per unit volume.

  2. Sample 2difficulty 2/5

    Which structural feature increases a cell's surface-area-to-volume ratio for efficient absorption?

    • A

      Smooth ER

    • B

      Microvilli

      check_circle
    • C

      Centrioles

    • D

      Nucleolus

    Why

    Microvilli are finger-like membrane projections (e.g., on intestinal epithelial cells) that dramatically expand absorptive surface.

  3. Sample 3difficulty 2/5

    virus ~50 nm bacterium ~1 μm animal cell ~10-30 μm

    Approximate ordering by size (smallest to largest) is

    • A

      Bacterium, virus, animal cell

    • B

      Animal cell, bacterium, virus

    • C

      Virus, bacterium, animal cell

      check_circle
    • D

      Same size

    Why

    Virus (<del>50 nm) << bacterium (</del>1 µm) << eukaryotic cell (~10 µm). Each scale step is roughly 10× larger.

  4. Sample 4difficulty 3/5

    Intestinal absorptive cells take up large amounts of glucose and amino acids per minute. EM images show their apical surfaces are densely packed with finger-like protrusions called microvilli. A textbook claims this increases absorption per unit area.

    Smooth cell low SA Cell with microvilli high SA Microvilli increase SA without increasing V

    Which statement BEST explains the functional advantage of microvilli for these cells?

    • A

      They allow the cell to switch between active and passive transport

    • B

      They increase the surface area available for transport without increasing cell volume

      check_circle
    • C

      They reduce overall surface area to limit ion leakage

    • D

      They increase the volume of the cell while keeping surface area constant

    Why

    Microvilli amplify membrane area; transport proteins on a larger surface boost net flux of nutrients without altering cell volume.

  5. Sample 5difficulty 3/5

    Three agar cubes (1, 2, 3 cm sides) in 0.1 M NaOH.

    Side SA (cm2) V (cm3) SA:V 1 cm 6 1 6.0 2 cm 24 8 3.0 3 cm 54 27 2.0 SA:V ratios

    Which biological principle does this experiment illustrate?

    • A

      Diffusion does not depend on geometry

    • B

      Cubic cells exist in nature

    • C

      Cells must remain small (or have folded membranes) to maintain efficient exchange with their environment

      check_circle
    • D

      Larger cells have higher diffusion rates

    Why

    As size increases, volume grows as L^3 while surface as L^2. The decreasing SA:V ratio limits exchange efficiency. This is why cells are small or have specialized surface elaborations (microvilli, alveoli, root hairs) to maintain exchange.